Ontogeny and cellular localization of SRY transcripts in the human testes and its detection in spermatozoa.

@article{Modi2005OntogenyAC,
  title={Ontogeny and cellular localization of SRY transcripts in the human testes and its detection in spermatozoa.},
  author={Deepak Modi and Charmi Shah and Geetanjali Sachdeva and Sushama Gadkar and Deepa Bhartiya and Christina Puri},
  journal={Reproduction},
  year={2005},
  volume={130 5},
  pages={603-13}
}
The sex-determining region on the Y (SRY) gene is unequivocally designated as the testis-determining factor in mammals; however, its roles beyond sex determination, if any, have been hitherto unknown. To determine whether SRY has any roles beyond sex determination, herein the expression of SRY mRNA was investigated in the midtrimester human fetal, infantile and adult testes as well as in ejaculated spermatozoa. High levels of SRY transcripts were in situ localized to the Sertoli cells of the… CONTINUE READING

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