Ontogenic expression of putative feeding peptides in the rat fetal brain and placenta.

@article{Beloosesky2006OntogenicEO,
  title={Ontogenic expression of putative feeding peptides in the rat fetal brain and placenta.},
  author={Ron Beloosesky and Dave A. Gayle and Fataneh Amidi and Sureshbabu N Ahanya and Mina Desai and Michael G. Ross},
  journal={Nutritional neuroscience},
  year={2006},
  volume={9 1-2},
  pages={33-40}
}
The well-demonstrated "fetal programming" paradigm is based on the observation that environmental changes can reset the developmental path and thus, gene expression during intrauterine development. As appetite-regulatory neural pathways develop in utero, we sought to determine the ontogenic expression of putative orexigenic and anorexigenic feeding-regulatory peptides in the fetal rat brain and placenta during the last third of gestation. Pregnant Sprague-Dawley rats (n = 12) at D14, D16 and… CONTINUE READING