Ontogenetic Patterning of Human Subchondral Bone Microarchitecture in the Proximal Tibia
@article{Goliath2022OntogeneticPO, title={Ontogenetic Patterning of Human Subchondral Bone Microarchitecture in the Proximal Tibia}, author={Jesse R. Goliath and James H. Gosman and Sam D. Stout and Timothy M Ryan}, journal={Biology}, year={2022}, volume={11} }
Simple Summary The objective of this study is to explain the subchondral trabecular and the cortical ontogenetic changes that occur in the proximal tibia in both the medial and lateral condylar regions due to differential loadings associated with changing knee joint kinetics and body mass. The differential response of subchondral bone to changing mechanical loads during growth and development serves as a powerful tool to evaluate the significance of mechanical loading on subchondral bone…
Figures and Tables from this paper
figure 1.1 figure 2.1 figure 2.2 figure 2.3 figure 2.4 figure 2.5 figure 2.6 figure 3.1 figure 4.1 figure 4.2 figure 4.3 figure 5.1 figure 5.10 figure 5.11 figure 5.12 figure 5.13 figure 5.14 figure 5.15 figure 5.16 figure 5.2 figure 5.3 figure 5.4 figure 5.5 figure 5.6 figure 5.7 figure 5.8 figure 5.9 figure 6.1 figure 6.10 figure 6.11 figure 6.12 figure 6.13 figure 6.14 figure 6.15 figure 6.16 figure 6.17 figure 6.18 figure 6.19 figure 6.2 figure 6.20 figure 6.21 figure 6.22 figure 6.23 figure 6.24 figure 6.25 figure 6.26 figure 6.3 figure 6.4 figure 6.5 figure 6.6 figure 6.7 figure 6.8 figure 6.9 table A.1 table A.1 table A.2 table A.3 table A.4 table A.5 table A.7 table A.7 table A.7 table A.8 table A.8 table A.9 table A.9 table B.1 table B.2 table B.3 table B.4 table B.6 table B.7
3 Citations
The developing juvenile distal tibia: Radiographic identification of distinct ontogenetic phases and structural trajectories
- BiologyJournal of anatomy
- 2022
Results showed that the perinatal tibia did not exhibit a rudimentary structural pattern similar to the architecture observed within the late adolescent tibia, suggesting a strong influence of biomechanical forces on the development of the distal tibia.
Development of a Bionic Tube with High Bending-Stiffness Properties Based on Human Tibiofibular Shapes
- Engineering, Materials ScienceBiomimetics
- 2023
This paper demonstrates that the bionic tube inspired by the human tibiofibular shape has excellent effectiveness and bending properties, and could be used in the fields of healthcare engineering, such as robotics and prosthetics.
Relationship between mechanical and microstructural parameters of rat lumbar spine in different ages.
- Biology, Materials ScienceComputer methods in biomechanics and biomedical engineering
- 2023
The tissue-level mechanical parameters, microstructure parameters of cancellous bone, and apparent mechanical parameters of L6 vertebral body were calculated in female SD rats aged 1, 3, 5, 7, 9, 11, 13, 15, 16, and 17-month-old to help understand the mechanism of osteoporotic fractures.
References
SHOWING 1-10 OF 349 REFERENCES
Development of Cortical Bone Geometry in the Human Femoral and Tibial Diaphysis
- MedicineAnatomical record
- 2013
The data reveal that the femoral and tibial midshaft shape are relatively conserved throughout growth; yet, conversely, the proximal and distal femoral diaphysis and proximal tibials appear more sensitive to developmentally induced changes in mechanical loading.
Microarchitectural adaptations in aging and osteoarthrotic subchondral bone issues
- Biology, MedicineActa orthopaedica. Supplementum
- 2010
The overall goals of the current series of studies were to investigate the age-related and osteoarthrosis related changes in the 3-D microarchitectural properties, mechanical properties, collagen and mineral quality of subchondral cancellous and cortical bone tissues.
Age-Related Three-Dimensional Microarchitectural Adaptations of Subchondral Bone Tissues in Guinea Pig Primary Osteoarthrosis
- Medicine, BiologyCalcified Tissue International
- 2005
Significant alterations of the microarchitecture and bone matrix composition of the subchondral bone did not appear to follow the same pattern as in normal aging and may have different influences on the resulting mechanical properties.
Trabecular bone ontogeny in the human proximal femur.
- Medicine, BiologyJournal of human evolution
- 2006
Changes in articular cartilage and subchondral bone histomorphometry in osteoarthritic knee joints in humans.
- Biology, MedicineBone
- 2003
Ontogenetic changes to bone microstructure in an archaeologically derived sample of human ribs
- BiologyJournal of anatomy
- 2019
Cortical porosity data are not correlated with two‐dimensional measures of osteon population density (OPD), which suggests that unfilled resorption spaces contribute more significantly to cortical porosity than do the Haversian canals of secondary osteons.
Topographical variations in articular cartilage and subchondral bone of the normal rat knee are age-related.
- Biology, MedicineAnnals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft
- 2014
Ontogenetic Patterning of Cortical Bone Microstructure and Geometry at the Human Mid‐Shaft Femur
- BiologyAnatomical record
- 2009
On the basis of the presence of transitional fibrolamellar bone complex, growth is more rapid during the toddler years and peri‐puberty, and slower in early to late childhood and in later adolescence.
Studies of tibial subchondral bone density and its significance.
- Biology, MedicineThe Journal of bone and joint surgery. American volume
- 1985
There is a trinitarian relationship between the meniscus, cartilage, and subchondral bone, in which structural changes in any one of the three causes secondary pathological adaptive changes in the other two.
Subchondral Bone Plate Changes More Rapidly than Trabecular Bone in Osteoarthritis
- Medicine, BiologyInternational journal of molecular sciences
- 2016
The rapid early changes in SbpTh, TbTh, Sbp BMD and Tb BMD in the disease prone DH guinea pigs compared with the BS2 control strain suggest a link to early OA pathology.