Online electrochemical systems for continuous neurochemical measurements with low-potential mediator-based electrochemical biosensors as selective detectors.

@article{Zhang2015OnlineES,
  title={Online electrochemical systems for continuous neurochemical measurements with low-potential mediator-based electrochemical biosensors as selective detectors.},
  author={Zipin Zhang and Jie Hao and Tongfang Xiao and Ping Yu and Lanqun Mao},
  journal={The Analyst},
  year={2015},
  volume={140 15},
  pages={5039-47}
}
This study demonstrates a new strategy to develop online electrochemical systems (OECSs) for continuously monitoring neurochemicals by efficiently integrating in vivo microdialysis with an oxidase-based electrochemical biosensor with low-potential electron mediators to shuttle the electron transfer of the oxidases. By using thionine and xanthine oxidase… CONTINUE READING