Onion peel extracts ameliorate hyperglycemia and insulin resistance in high fat diet/streptozotocin-induced diabetic rats

@inproceedings{Jung2011OnionPE,
  title={Onion peel extracts ameliorate hyperglycemia and insulin resistance in high fat diet/streptozotocin-induced diabetic rats},
  author={Ji young Jung and Yeni Lim and Min Sun Moon and Ji Yeon Kim and Oran Kwon},
  booktitle={Nutrition & metabolism},
  year={2011}
}
BackgroundQuercetin derivatives in onions have been regarded as the most important flavonoids to improve diabetic status in cells and animal models. The present study was aimed to examine the hypoglycemic and insulin-sensitizing capacity of onion peel extract (OPE) containing high quercetin in high fat diet/streptozotocin-induced diabetic rats and to elucidate the mechanism of its insulin-sensitizing effect.MethodsMale Sprague-Dawley rats were fed the AIN-93G diet modified to contain 41.2% fat… CONTINUE READING

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