Ongoing purifying selection on intergenic spacers in group A streptococcus.


Bacterial intergenic spacers are non-coding genomic regions enriched with cis-regulatory elements for gene expression. A population genetics approach was used to investigate the evolutionary force shaping the genetic diversity of intergenic spacers among 13 genomes of group A streptococcus (GAS). Analysis of 590 genes and their linked 5' intergenic spacers… (More)
DOI: 10.1016/j.meegid.2010.11.005

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