Ongoing V kappa-J kappa recombination after formation of a productive V kappa-J kappa coding joint.

@article{Huber1992OngoingVK,
  title={Ongoing V kappa-J kappa recombination after formation of a productive V kappa-J kappa coding joint.},
  author={Claudia Huber and H. G. Klobeck and H. G. Zachau},
  journal={European journal of immunology},
  year={1992},
  volume={22 6},
  pages={1561-5}
}
V kappa genes of man can recombine with the J kappa gene segments either by an inversion or by a deletion mechanism. Back-to-back fusion products of the respective recombination signal sequences (signal joints) are retained on the chromosome after the formation of a V kappa-J kappa coding joint by an inversion. Our knowledge of the structure of the human… CONTINUE READING