One year treatment with almitrine improves hypoxaemia but does not increase pulmonary artery pressure in COPD patients.

@article{Weitzenblum1991OneYT,
  title={One year treatment with almitrine improves hypoxaemia but does not increase pulmonary artery pressure in COPD patients.},
  author={Emmanuel Weitzenblum and Francine Schrijen and M. Apprill and Christian G. Prefaut and J. C. Yernault},
  journal={The European respiratory journal},
  year={1991},
  volume={4 10},
  pages={1215-22}
}
Almitrine bismesylate, a chemoreceptor agonist, improves hypoxaemia in a high percentage of chronic obstructive pulmonary disease (COPD) patients and its long-term use may thus be of interest in these patients. The course of pulmonary haemodynamics during a one year treatment was investigated in severe COPD patients (forced expiratory volume in one second FEV1 = 1,040 +/- 80 SEM ml) with persistent hypoxaemia (initial arterial oxygen tension (PaO2) in the range 6.6-8.6 kPa (50-65 mmHg… CONTINUE READING
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