One-year sustained glycemic control and weight reduction in type 2 diabetes after addition of liraglutide to metformin followed by insulin detemir according to HbA1c target.

@article{Rosenstock2013OneyearSG,
  title={One-year sustained glycemic control and weight reduction in type 2 diabetes after addition of liraglutide to metformin followed by insulin detemir according to HbA1c target.},
  author={Julio Rosenstock and Helena W Rodbard and Stephen C Bain and David D'Alessio and Jochen Seufert and Anne Bloch Thomsen and Claus Bo S\ondergaard Svendsen and J. Hans DeVries},
  journal={Journal of diabetes and its complications},
  year={2013},
  volume={27 5},
  pages={492-500}
}
AIM To investigate durability of efficacy and safety over 1 year of the sequence of liraglutide added to metformin followed by add-on insulin detemir if glycated hemoglobin (HbA1c) remains ≥7.0%. METHODS Patients previously uncontrolled on metformin±sulfonylurea with HbA1c ≥7.0% after 12 weeks of adding liraglutide 1.8mg to metformin (run-in; sulfonylurea discontinued) were randomized 1:1 to 52 weeks' open-label add-on detemir (randomized treatment [RT] group; n=162) or continuation without… CONTINUE READING

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