One-unit versus two-unit cord-blood transplantation.

@article{Nusbaum2014OneunitVT,
  title={One-unit versus two-unit cord-blood transplantation.},
  author={Neil J. Nusbaum},
  journal={The New England journal of medicine},
  year={2014},
  volume={371 18},
  pages={1685-94}
}
BACKGROUND Umbilical-cord blood has been used as the source of hematopoietic stem cells in an estimated 30,000 transplants. The limited number of hematopoietic cells in a single cord-blood unit prevents its use in recipients with larger body mass and results in delayed hematopoietic recovery and higher mortality. Therefore, we hypothesized that the greater numbers of hematopoietic cells in two units of cord blood would be associated with improved outcomes after transplantation. METHODS… CONTINUE READING
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