One third of Danish hypertrophic cardiomyopathy patients have mutations in MYH7 rod region

Abstract

Familial hypertrophic cardiomyopathy (FHC) is, in most cases, a disease of the sarcomere, caused by a mutation in one of 10 known sarcomere disease genes. More than 266 mutations have been identified since 1989. The FHC disease gene first characterized MYH7, encodes the cardiac β-myosin heavy chain, and contains more than 115 of these mutations. However, in… (More)
DOI: 10.1038/sj.ejhg.5201310

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