One-step separation of four flavonoids from Herba Salviae Plbeiae by HSCCC.

@article{Li2014OnestepSO,
  title={One-step separation of four flavonoids from Herba Salviae Plbeiae by HSCCC.},
  author={Jia Li and Xiao-You Zhang and Qi Yu and Xiaohui Fu and Weina Wang},
  journal={Journal of chromatographic science},
  year={2014},
  volume={52 10},
  pages={
          1288-93
        }
}
High-speed countercurrent chromatography (HSCCC) was successfully applied to the isolation and purification of four flavonoids from Herba Salviae Plbeiae using stepwise and dual-mode elution with a pair of two-phase solvent systems. The systems composed of n-hexane-chloroform-methanol-water (0.5 : 4 : 3 : 2, v/v/v/v) and chloroform-methanol-water (4 : 3 : 2, v/v/v). Analytical HSCCC was used for the preliminary selection of a suitable system, and a linear scale-step procedure was performed at a… 
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