One-step purification and concentration of DNA in porous membranes for point-of-care applications.

@article{Byrnes2015OnestepPA,
  title={One-step purification and concentration of DNA in porous membranes for point-of-care applications.},
  author={Samantha A. Byrnes and Joshua D. Bishop and L Lafleur and Joshua R. Buser and Barry Lutz and Paul Yager},
  journal={Lab on a chip},
  year={2015},
  volume={15 12},
  pages={2647-59}
}
The emergence of rapid, user-friendly, point-of-care (POC) diagnostic systems is paving the way for better disease diagnosis and control. Lately, there has been a strong emphasis on developing molecular-based diagnostics due to their potential for greatly increased sensitivity and specificity. One of the most critical steps in developing practical diagnostic systems is the ability to perform sample preparation, especially the purification of nucleic acids (NA), at the POC. As such, we have… CONTINUE READING