One-step labeling of degenerative neurons in unfixed brain tissue samples using Fluoro-Jade C.

@article{Gu2012OnestepLO,
  title={One-step labeling of degenerative neurons in unfixed brain tissue samples using Fluoro-Jade C.},
  author={Qiang Gu and Larry C. Schmued and Sumit Sarkar and Merle G. Paule and Bryan Raymick},
  journal={Journal of neuroscience methods},
  year={2012},
  volume={208 1},
  pages={40-3}
}
Neurodegeneration is the underlying cause of a vast majority of neurological disorders and often a result of brain trauma, stroke, or neurotoxic insult. Here we describe a simple method for labeling degenerating neurons in unfixed brain tissue samples. This method could provide a new avenue for identifying and harvesting degenerative neurons from unfixed brain tissues for subsequent molecular analyses. 
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Fluoro - Jade dyes : fluorochromes for the histochemical localization of degenerative neurons

  • S Sarkar, L Schmued
  • J Alzheimers Dis
  • 2011
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