One single in-frame AUG codon is responsible for a diversity of subcellular localizations of glutaredoxin 2 in Saccharomyces cerevisiae.

@article{Porras2006OneSI,
  title={One single in-frame AUG codon is responsible for a diversity of subcellular localizations of glutaredoxin 2 in Saccharomyces cerevisiae.},
  author={P. Porras and C. Alicia Padilla and Martin Krayl and Wolfgang Voos and Jose Antonio Velasco Barcena},
  journal={The Journal of biological chemistry},
  year={2006},
  volume={281 24},
  pages={16551-62}
}
Glutaredoxins belong to a family of small proteins with glutathione-dependent disulfide oxidoreductase activity involved in cellular defense against oxidative stress. The product of the yeast GRX2 gene is a protein that is localized both in the cytosol and mitochondria. To throw light onto the mechanism responsible for the dual subcellular distribution of Grx2 we analyzed mutant constructs containing different targeting information. By altering amino acid residues around the two in-frame… CONTINUE READING

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