One-pot direct C-H arylation of arenes in water catalysed by RuCl3·nH2O-NaOAc in the presence of Zn.

Abstract

The inexpensive and commercially available catalytic system RuCl3·nH2O-NaOAc-Zn is active in water for the direct C-H arylation of arenes with aryl/heteroaryl chlorides. The reaction can be accelerated by the use of microwave irradiation and can also be scaled up to a multi-gram scale with excellent isolated yields. 
DOI: 10.1039/c3cc43452d

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