One lipid, multiple functions: how various pools of PI(4,5)P2 are created in the plasma membrane

Abstract

Phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2] is a minor lipid of the inner leaflet of the plasma membrane that controls the activity of numerous proteins and serves as a source of second messengers. This multifunctionality of PI(4,5)P2 relies on mechanisms ensuring transient appearance of PI(4,5)P2 clusters in the plasma membrane. One such mechanism… (More)
DOI: 10.1007/s00018-010-0432-5

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Cite this paper

@article{Kwiatkowska2010OneLM, title={One lipid, multiple functions: how various pools of PI(4,5)P2 are created in the plasma membrane}, author={Katarzyna Kwiatkowska}, journal={Cellular and Molecular Life Sciences}, year={2010}, volume={67}, pages={3927-3946} }