One hundred years of poliovirus pathogenesis.

@article{Racaniello2006OneHY,
  title={One hundred years of poliovirus pathogenesis.},
  author={Vincent R. Racaniello},
  journal={Virology},
  year={2006},
  volume={344 1},
  pages={9-16}
}
Poliovirus was first isolated nearly 100 years ago in a landmark experiment that established the viral etiology of poliomyelitis. This discovery stimulated investigation of the pathogenesis of poliomyelitis in many laboratories. Nearly 50 years later, when two effective poliovirus vaccines were developed, the impetus to study poliovirus pathogenesis waned. The identification of the cell receptor for poliovirus, CD155, and its use in the development of transgenic mice susceptible to poliovirus… CONTINUE READING

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Picornaviridae: the viruses and their replication

  • V. R. Racaniello
  • VOLS
  • 2001
Highly Influential
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