One-hour rule-out and rule-in of acute myocardial infarction using high-sensitivity cardiac troponin T.

@article{Reichlin2012OnehourRA,
  title={One-hour rule-out and rule-in of acute myocardial infarction using high-sensitivity cardiac troponin T.},
  author={Tobias Reichlin and Christian Schindler and Beatrice Drexler and Raphael Twerenbold and Miriam Reiter and Christa Zellweger and Berit Moehring and Ronny Ziller and Rebeca Hoeller and Mar{\'i}a Rubini Gim{\'e}nez and Philip Haaf and Mihael Potocki and Karin Wildi and Catharina Balmelli and Michael Freese and Claudia Stelzig and Heike Freidank and Stefan O\sswald and Christian M{\"u}ller},
  journal={Archives of internal medicine},
  year={2012},
  volume={172 16},
  pages={1211-8}
}
BACKGROUND High-sensitivity cardiac troponin (hs-cTn) assays seem to improve the early diagnosis of acute myocardial infarction (AMI), but it is unknown how to best use them in clinical practice. Our objective was to develop and validate an algorithm for rapid rule-out and rule-in of AMI. METHODS A prospective multicenter study enrolling 872 unselected patients with acute chest pain presenting to the emergency department. High-sensitivity cardiac troponin T (hs-cTnT) was measured in a blinded… CONTINUE READING
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