One-dimensional Brownian motion of charged nanoparticles along microtubules: a model system for weak binding interactions.

@article{Minoura2010OnedimensionalBM,
  title={One-dimensional Brownian motion of charged nanoparticles along microtubules: a model system for weak binding interactions.},
  author={Itsushi Minoura and Eisaku Katayama and Ken Sekimoto and Etsuko Muto},
  journal={Biophysical journal},
  year={2010},
  volume={98 8},
  pages={1589-97}
}
Various proteins are known to exhibit one-dimensional Brownian motion along charged rodlike polymers, such as microtubules (MTs), actin, and DNA. The electrostatic interaction between the proteins and the rodlike polymers appears to be crucial for one-dimensional Brownian motion, although the underlying mechanism has not been fully clarified. We examined the interactions of positively-charged nanoparticles composed of polyacrylamide gels with MTs. These hydrophilic nanoparticles bound to MTs… CONTINUE READING