One day of overfeeding impairs nocturnal glucose but not fatty acid homeostasis in overweight men

@inproceedings{Magkos2014OneDO,
  title={One day of overfeeding impairs nocturnal glucose but not fatty acid homeostasis in overweight men},
  author={Faidon Magkos and Gordon I. Smith and Dominic N. Reeds and Adewole L Okunade and Bruce W. Patterson and Bettina Mittendorfer},
  booktitle={Obesity},
  year={2014}
}
OBJECTIVE Overfeeding is associated with insulin resistance. Studies on animals suggest this is likely due to disruption of fatty acid metabolism and increased plasma free fatty acid (FFA) availability during the night. We tested the hypothesis that overfeeding induces insulin resistance and increases nocturnal but not daytime plasma FFA availability in human subjects. DESIGN AND METHODS We measured plasma glucose, insulin, and FFA concentrations hourly for 24 h during a day of isocaloric… CONTINUE READING
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