One-carbon metabolism enzyme polymorphisms and uteroplacental insufficiency.

  title={One-carbon metabolism enzyme polymorphisms and uteroplacental insufficiency.},
  author={Denise L Furness and Michael F. Fenech and Yee T Khong and Roberto Romero and Gustaaf Dekker},
  journal={American journal of obstetrics and gynecology},
  volume={199 3},
OBJECTIVES This study was undertaken to test novel genetic polymorphisms involved in 1-carbon metabolism for a potential association with increased risk of developing pregnancy complications associated with uteroplacental insufficiency. STUDY DESIGN This was a prospective cohort study consisting of 50 women at low risk and 93 women at high risk for having a pregnancy complication develop. Maternal and fetal DNA samples were genotyped for methionine synthase (MTR) A2756G, methionine synthase… CONTINUE READING
20 Citations
34 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 20 extracted citations


Publications referenced by this paper.
Showing 1-10 of 34 references

Dietary intake f folate and cofactors in folate metabolism , THFR polymorphisms , and reduced rectal ancer

  • E Also-Rallo, E Lopez-Quesada, R Urreizti, MA ilaseca, JM Lailla, S Balcells
  • Cancer Causes Control
  • 2007

mpact of folate and homocysteine metabolism n human reproductive health

  • M Kimura, K Umegaki, M Higuchi, P Thomas, M enech
  • Hum Reprod pdate
  • 2007

Confirmation f the R 653 Q polymorphism of the trifunctional 1 - synthase enzyme as a maternal risk for neu - al tube defects in the Irish population

  • A Parle-McDermott, JL Mills, PN Kirke, CC Signore, S Kirke
  • Eur J um Genet
  • 2006

MTHFD 1 R 653 Q olymorphism is a maternal genetic risk factor or severe abruptio placentae

  • MA Brown, J Higgins, S Lowe
  • Am J Med Genet
  • 2005

Poly - orphisms of genes involved in homocysteine etabolism in preeclampsia and in uncompli - ated pregnancies

  • VB O’Leary, A Parle-McDermott, AM Molloy, PM irke, Z Johnson, M Conley
  • Eur J Obstet Gynecol Re - rod Biol
  • 2005

The methionine synthase olymorphism c . 2756 Aright curved arrow G D 919 G ) is relevant for disease - free longevity

  • CL Drennan, S Huang, JT Drummon, ML Lidwig
  • nt J Mol Med
  • 2005

Similar Papers

Loading similar papers…