One-Pot Synthesis of Novel Spiro[quinazoline/pyrimidine]ones via Multi Component Reaction

  title={One-Pot Synthesis of Novel Spiro[quinazoline/pyrimidine]ones via Multi Component Reaction},
  author={Gangadhar Meshram and P. Wagh and Shruti S. Deshpande and Vipul Amratlal},
  journal={Letters in Organic Chemistry},
5 Citations
Recent Developments in Acenaphthoquinone-Based Multicomponent Reactions: Synthesis of Spiroacenaphthylene Compounds
This review characterizes the multicomponent reactions of acenaphthoquinone as building blocks for the synthesis of a variety of heterocyclic compounds with medicinal chemistry interest. There is a
Synthesis of New Functionally Substituted Aryl- and Hetarylcarbamates Based on Ninhydrin
The condensation of methyl (ethyl) phenylcarbamates with ninhydrin in concentrated sulfuric acid gave dialkyl [1,3-dioxoindan-2,2-diyldi(4,1-phenylene)]biscarbamates. Treatment of the latter with
A catalyst-free, one-pot multicomponent synthesis of spiro-benzimidazoquinazolinones via a Knoevenagel–Michael-imine pathway: a microwave assisted approach
A novel multi-component route for the synthesis of spiro-benzimidazoquinazolinones has been developed under microwave irradiation. It involves a one-pot three-component reaction of acenaphthoquinone
Recent applications of barbituric acid in multicomponent reactions
Barbituric acid has been utilized in the design and synthesis of diverse types of heterocyclic and carbocyclic compounds and considered as an important building block in organic synthesis. There is a
One‐Pot Synthesis of Novel Spiro[quinazoline/pyrimidine]ones via Multi Component Reaction.
A new and facile one-pot method for synthesis of the title scaffolds is presented and further extended by employing two other reactive ketones instead of isatin.