One Nucleotide in a κB Site Can Determine Cofactor Specificity for NF-κB Dimers

  title={One Nucleotide in a κB Site Can Determine Cofactor Specificity for NF-κB Dimers},
  author={Thomas Ho-Yin Leung and Alexander Hoffmann and David Baltimore},
the NFB family are involved in gene activation: p50, p52, p65, and cRel. They are the mature gene products from four genes: nfkB1, nfkB2, relA, and rel, respectively, Thomas H. Leung,1 Alexander Hoffmann,1,2 and David Baltimore1,* Division of Biology and they homoor heterodimerize with one another to California Institute of Technology bind DNA. It is noteworthy that mice deficient in a single Pasadena, California 91125 NFB/Rel family member exhibit unique, largely nonoverlapping phenotypes. For… CONTINUE READING
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Inhibiting of NF - kappaB / Rel transcription factors defines functional specifici - HIV - 1 infection in human T cells by lentiviral - mediated delivery of ties

  • A. Hoffmann, T. H. Leung, D. Baltimore, X. F. Qin, D. S. An, I. S. Chen
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