Oncotic pressure in solid tumors is elevated.

  title={Oncotic pressure in solid tumors is elevated.},
  author={Manfred Stohrer and Yves Boucher and Manfred Stangassinger and Rakesh K. Jain},
  journal={Cancer research},
  volume={60 15},
Oncotic and hydrostatic pressure differences control the movement of fluid and large molecules across the microvascular wall of normal and tumor tissues. Recent studies have shown that the interstitial fluid pressure in tumors is elevated and is approximately equal to the microvascular pressure. Whereas oncotic pressure in blood plasma of various species is known, no data are available on the oncotic pressure in the interstitial space of tumors. We hypothesize that because of the leaky nature… CONTINUE READING
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