Oncostatin-M promotes phenotypic changes associated with mesenchymal and stem cell-like differentiation in breast cancer

@article{West2014OncostatinMPP,
  title={Oncostatin-M promotes phenotypic changes associated with mesenchymal and stem cell-like differentiation in breast cancer},
  author={Nathan R. West and J. Ivor Murray and Peter Hamilton Watson},
  journal={Oncogene},
  year={2014},
  volume={33},
  pages={1485-1494}
}
Cancer stem cell (CSC) biology and the epithelial-to-mesenchymal transition (EMT) are thought to be mechanistically linked and may be key components of cancer development and progression. However, stimuli that induce EMT and CSC-like features (‘stemness’) are poorly defined. We and others have shown that the inflammatory cytokine oncostatin-M (OSM) mediates phenotypic changes in breast cancer that are consistent with EMT and dedifferentiation, including enhanced migration and loss of hormone… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS
32 Citations
62 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 32 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 62 references

Similar Papers

Loading similar papers…