Onconase, a cytotoxic ribonuclease, in combination with standard of care agents in non-small cell lung tumorgraft models.

Abstract

e13520 Background: Onconase is a cytotoxic amphibian ribonuclease of the RNAse A superfamily. It is currently being evaluated in phase I/II trials and has been shown to possess anti-tumor activity in many preclinical studies. In an effort to identify clinical indications for Onconase, non-small cell lung tumografts were treated with a combination of… (More)

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.