Oncomirs — microRNAs with a role in cancer

@article{EsquelaKerscher2006OncomirsM,
  title={Oncomirs — microRNAs with a role in cancer},
  author={Aurora Esquela-Kerscher and Frank J. Slack},
  journal={Nature Reviews Cancer},
  year={2006},
  volume={6},
  pages={259-269}
}
MicroRNAs (miRNAs) are an abundant class of small non-protein-coding RNAs that function as negative gene regulators. They regulate diverse biological processes, and bioinformatic data indicates that each miRNA can control hundreds of gene targets, underscoring the potential influence of miRNAs on almost every genetic pathway. Recent evidence has shown that miRNA mutations or mis-expression correlate with various human cancers and indicates that miRNAs can function as tumour suppressors and… Expand

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