Oncolytic viruses as novel anticancer agents: turning one scourge against another.

@article{Smith2000OncolyticVA,
  title={Oncolytic viruses as novel anticancer agents: turning one scourge against another.},
  author={Edward R Smith and E. A. Chiocca},
  journal={Expert opinion on investigational drugs},
  year={2000},
  volume={9 2},
  pages={311-27}
}
Although the use of viruses as oncolytic agents is an historic concept, the use of genetically modified viruses to selectively target tumour cells is relatively novel and recent. The ability of viruses to efficiently infect and lyse cells, combined with the potential augmentation of this effect by progeny viruses throughout the tumour provide justification… CONTINUE READING