Oncolytic vesicular stomatitis virus for treatment of orthotopic hepatocellular carcinoma in immune-competent rats.

@article{Ebert2003OncolyticVS,
  title={Oncolytic vesicular stomatitis virus for treatment of orthotopic hepatocellular carcinoma in immune-competent rats.},
  author={Oliver Ebert and Katsunori Shinozaki and Tian-gui Huang and Mikko J Savontaus and Adolfo Garc{\'i}a-Sastre and Savio L. C. Woo},
  journal={Cancer research},
  year={2003},
  volume={63 13},
  pages={3605-11}
}
Tumor-targeted replicating viruses are being developed as a novel class of oncolytic agents. Vesicular stomatitis virus (VSV) is a negative-strand RNA virus with inherent specificity for replication in tumor cells due to their attenuated antiviral responses. VSV as an oncolytic virus is particularly appealing for its exceptionally rapid replication rate in tumor cells, such that the oncolytic effects could be maximally manifested before the onset of potentially neutralizing antiviral immune… CONTINUE READING
55 Citations
27 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 55 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 27 references

A genetically engineered influenza A virus with ras-dependent oncolytic properties

  • M. Bergmann, I. Romirer, +7 authors T. Muster
  • Cancer Res.,
  • 2003
1 Excerpt

Similar Papers

Loading similar papers…