Oncolytic Reovirus in Canine Mast Cell Tumor

  title={Oncolytic Reovirus in Canine Mast Cell Tumor},
  author={Chung Chew Hwang and Saori Umeki and Masahito Mogami Kubo and Toshiharu Hayashi and Hiroshi Shimoda and Masami Mochizuki and Ken Maeda and Kenji Baba and Hiroko Hiraoka and Matthew C. Coffey and Masaru Okuda and Takuya Mizuno},
  booktitle={PloS one},
The usage of reovirus has reached phase II and III clinical trials in human cancers. However, this is the first study to report the oncolytic effects of reovirus in veterinary oncology, focusing on canine mast cell tumor (MCT), the most common cutaneous tumor in dogs. As human and canine cancers share many similarities, we hypothesized that the oncolytic effects of reovirus can be exploited in canine cancers. The objective of this study was to determine the oncolytic effects of reovirus in… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 7 times. VIEW TWEETS


Publications citing this paper.
Showing 1-10 of 11 extracted citations

The oncolytic effects of reovirus in canine solid tumor cell lines

The Journal of veterinary medical science • 2015
View 9 Excerpts


Publications referenced by this paper.
Showing 1-10 of 51 references

Identification of c-kit mutations-independent neoplastic cell proliferation of canine mast cells.

Veterinary immunology and immunopathology • 2008
View 12 Excerpts
Highly Influenced

IgG-mediated histamine release from canine mastocytoma-derived cells.

International archives of allergy and immunology • 2001
View 9 Excerpts
Highly Influenced

Epidemiology and the evidence-based medicine approach

LM Butler, BN Bonnett, RL Page
View 1 Excerpt

Mast cell tumors

CA London, DH Thamm
View 2 Excerpts

Similar Papers

Loading similar papers…