Oncolytic Reovirus in Canine Mast Cell Tumor

@inproceedings{Hwang2013OncolyticRI,
  title={Oncolytic Reovirus in Canine Mast Cell Tumor},
  author={Chung Chew Hwang and Saori Umeki and Masahito Mogami Kubo and Toshiharu Hayashi and Hiroshi Shimoda and Masami Mochizuki and Ken Maeda and Kenji Baba and Hiroko Hiraoka and Matthew C. Coffey and Masaru Okuda and Takuya Mizuno},
  booktitle={PloS one},
  year={2013}
}
The usage of reovirus has reached phase II and III clinical trials in human cancers. However, this is the first study to report the oncolytic effects of reovirus in veterinary oncology, focusing on canine mast cell tumor (MCT), the most common cutaneous tumor in dogs. As human and canine cancers share many similarities, we hypothesized that the oncolytic effects of reovirus can be exploited in canine cancers. The objective of this study was to determine the oncolytic effects of reovirus in… CONTINUE READING
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