Oncologic Outcomes of Sporadic, Neurofibromatosis-Associated, and Radiation-Induced Malignant Peripheral Nerve Sheath Tumors

@article{Lafemina2012OncologicOO,
  title={Oncologic Outcomes of Sporadic, Neurofibromatosis-Associated, and Radiation-Induced Malignant Peripheral Nerve Sheath Tumors},
  author={Jennifer Lafemina and L Qin and MA NicoleH.Moraco and Cristina R Antonescu and Ryan Courtney Fields and PhD FACS Aimee M. Crago and Murray F. Brennan and Samuel Singer},
  journal={Annals of Surgical Oncology},
  year={2012},
  volume={20},
  pages={66-72}
}
Malignant peripheral nerve sheath tumors (MPNSTs) occur sporadically, after prior radiation therapy (RT), or in association with neurofibromatosis type 1 (NF1). It is controversial whether patients with NF1-associated MPNST have worse outcomes. We investigated the prognostic significance of sporadic, NF1-associated, and RT-induced MPNST. Patients with primary high-grade MPNST from 1982 to 2011 were identified from a prospectively maintained database. Patients with sporadic MPNST were included… CONTINUE READING
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