Oncogenicity of the transcription factor SOX8 in hepatocellular carcinoma

  title={Oncogenicity of the transcription factor SOX8 in hepatocellular carcinoma},
  author={Siquan Zhang and Cong Ling Zhu and Limin Zhu and Huafeng Liu and Shourong Liu and Nianbo Zhao and Jing Wu and Xiaoxiao Huang and Yujuan Zhang and Jie Jin and Ting Hong Ji and Xianfeng Ding},
  journal={Medical Oncology},
AbstractSOX genes play an important role in a number of developmental processes. SOXs have been demonstrated to have potential roles as either tumor suppressors or promoters in various neoplastic tissues depending on the tumor status and type. The aim of this study was to investigate the functional role of SOXs in human cancers. Gene expression changes of SOXs in human hepatocellular carcinoma (HCC) tissues were detected using real-time quantitative reverse transcriptase-polymerase chain… CONTINUE READING

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