Oncogenic potential of hepatitis B virus.

  title={Oncogenic potential of hepatitis B virus.},
  author={Katsuro Koike and Y. Shirakata and Katsuyuki Yaginuma and M Arii and Shinako Takada and Izuru Nakamura and Yasuhide Hayashi and Minako Kawada and Midori Kobayashi},
  journal={Molecular biology & medicine},
  volume={6 2},
The function of the X gene was clarified by examination of the transient production of hepatitis B virus (HBV) particles by transfected recombinant HBV DNA (pHBV-3 DNA) and its frameshift mutant (delta X) of the X open reading frame into hepatocellular carcinoma HuH-7 and HepG2 cells. No reduction of viral mRNAs was observed in the HuH-7 cells by the delta… CONTINUE READING