Oncogenes and cancer.

@article{Croce2008OncogenesAC,
  title={Oncogenes and cancer.},
  author={C. Croce},
  journal={The New England journal of medicine},
  year={2008},
  volume={358 5},
  pages={
          502-11
        }
}
  • C. Croce
  • Published 2008
  • Biology, Medicine
  • The New England journal of medicine
    • This review — the first in a series concerning the biology of cancer — is a comprehensive survey of oncogenes, tumor-suppressor genes, and microRNA genes in cancer cells. Work on the recently discovered microRNA genes in malignant cells has revealed new complexities in the regulation of oncogenes and tumor-suppressor genes and new opportunities for the treatment of cancer. 
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    References

    SHOWING 1-10 OF 85 REFERENCES
    Molecular themes in oncogenesis
    • 1,576
    MicroRNA signatures in human cancers
    • 6,631
    • PDF
    The Role of PML in Tumor Suppression
    • 549
    ras and human tumors.
    • 236
    Molecular abnormalities in lung cancer.
    • R. Salgia, A. Skarin
    • Medicine
    • Journal of clinical oncology : official journal of the American Society of Clinical Oncology
    • 1998
    • 227
    RAS and leukemia: from basic mechanisms to gene-directed therapy.
    • D. Beaupre, R. Kurzrock
    • Biology, Medicine
    • Journal of clinical oncology : official journal of the American Society of Clinical Oncology
    • 1999
    • 198
    Targeting the BCR-ABL tyrosine kinase in chronic myeloid leukemia.
    • 245
    Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue
    • 829
    Mutations of the BRAF gene in human cancer
    • 8,690
    • PDF
    AP-1 as a regulator of cell life and death
    • 2,388