Oncogenes and cancer.

@article{Croce2008OncogenesAC,
  title={Oncogenes and cancer.},
  author={C. Croce},
  journal={The New England journal of medicine},
  year={2008},
  volume={358 5},
  pages={
          502-11
        }
}
  • C. Croce
  • Published 2008
  • Biology, Medicine
  • The New England journal of medicine
    • This review — the first in a series concerning the biology of cancer — is a comprehensive survey of oncogenes, tumor-suppressor genes, and microRNA genes in cancer cells. Work on the recently discovered microRNA genes in malignant cells has revealed new complexities in the regulation of oncogenes and tumor-suppressor genes and new opportunities for the treatment of cancer. 
    View PDF
    686 Citations
    Highly Influencial Citations
    32
    Background Citations
    290
    Methods Citations
    4

    Figures, Tables, and Topics from this paper

    Figures and Tables

    Explore Further: Topics Discussed in This Paper

    Paper Mentions

    Interventional Clinical Trial
    Study of Debio 0932 in Patients With Advanced Solid Tumours or Lymphoma
    The purpose of this study is to determine the maximum tolerated dose of Debio 0932 when administered orally, every-other-day or daily during the first 30 days, in patients with… Expand
    ConditionsCancer, Lymphoma, Neoplasms, (+1 more)
    InterventionDrug
    Debiopharm International SA
    April 2010 - April 2013
    686 Citations
    Citation Type

    Citation Type

    Oncogenes as Therapeutic Targets in Cancer: A Review
    • 2
    • PDF
    Oncogenes - the basics
    • Highly Influenced
    • PDF
    Oncomirs: from tumor biology to molecularly targeted anticancer strategies.
    • 46
    • PDF
    Viral and Nonviral Oncogene Theories of Cancer
    • 2
    • Highly Influenced
    • PDF
    Principles of Cancer Pathogenesis and Therapies: A Brief Overview
    Neoplasia from genetic point of view.
    • 2
    Molecular Mechanism of Carcinogenesis
    Causes and consequences of microRNA dysregulation in cancer
    • C. Croce
    • Biology, Medicine
    • Nature Reviews Genetics
    • 2009
    • 2,572
    • PDF
    Nuclear Oncology 1: Principles of Tumor Pathology and Biology
    • 1
    Genes responsible for cancer: a review

    References

    SHOWING 1-10 OF 85 REFERENCES
    Molecular themes in oncogenesis
    • 1,576
    MicroRNA signatures in human cancers
    • 6,632
    • PDF
    The Role of PML in Tumor Suppression
    • 549
    ras and human tumors.
    • 236
    Molecular abnormalities in lung cancer.
    • R. Salgia, A. Skarin
    • Medicine
    • Journal of clinical oncology : official journal of the American Society of Clinical Oncology
    • 1998
    • 227
    RAS and leukemia: from basic mechanisms to gene-directed therapy.
    • D. Beaupre, R. Kurzrock
    • Biology, Medicine
    • Journal of clinical oncology : official journal of the American Society of Clinical Oncology
    • 1999
    • 198
    Targeting the BCR-ABL tyrosine kinase in chronic myeloid leukemia.
    • 245
    Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue
    • 829
    Mutations of the BRAF gene in human cancer
    • 8,690
    • PDF
    AP-1 as a regulator of cell life and death
    • 2,388