Oncogenes and cancer.
@article{Croce2008OncogenesAC, title={Oncogenes and cancer.}, author={C. Croce}, journal={The New England journal of medicine}, year={2008}, volume={358 5}, pages={ 502-11 } }
This review — the first in a series concerning the biology of cancer — is a comprehensive survey of oncogenes, tumor-suppressor genes, and microRNA genes in cancer cells. Work on the recently discovered microRNA genes in malignant cells has revealed new complexities in the regulation of oncogenes and tumor-suppressor genes and new opportunities for the treatment of cancer.
Figures, Tables, and Topics from this paper
Paper Mentions
Interventional Clinical Trial
The purpose of this study is to determine the maximum tolerated dose of Debio 0932 when
administered orally, every-other-day or daily during the first 30 days, in patients with… Expand
Conditions | Cancer, Lymphoma, Neoplasms, (+1 more) |
---|---|
Intervention | Drug |
686 Citations
Oncomirs: from tumor biology to molecularly targeted anticancer strategies.
- Biology, Medicine
- Mini reviews in medicinal chemistry
- 2009
- 46
- PDF
Causes and consequences of microRNA dysregulation in cancer
- Biology, Medicine
- Nature Reviews Genetics
- 2009
- 2,572
- PDF
References
SHOWING 1-10 OF 85 REFERENCES
Molecular abnormalities in lung cancer.
- Medicine
- Journal of clinical oncology : official journal of the American Society of Clinical Oncology
- 1998
- 227
RAS and leukemia: from basic mechanisms to gene-directed therapy.
- Biology, Medicine
- Journal of clinical oncology : official journal of the American Society of Clinical Oncology
- 1999
- 198
Targeting the BCR-ABL tyrosine kinase in chronic myeloid leukemia.
- Medicine
- The New England journal of medicine
- 2001
- 245
Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue
- Biology, Medicine
- Nature
- 1983
- 829