Oncogenes: The Passport for Viral Oncolysis Through PKR Inhibition

Abstract

The transforming properties of oncogenes are derived from gain-of-function mutations, shifting cell signaling from highly regulated homeostatic to an uncontrolled oncogenic state, with the contribution of the inactivating mutations in tumor suppressor genes P53 and RB, leading to tumor resistance to conventional and target-directed therapy. On the other… (More)
DOI: 10.4137/BIC.S33378

Topics

1 Figure or Table

Cite this paper

@inproceedings{Fernandes2016OncogenesTP, title={Oncogenes: The Passport for Viral Oncolysis Through PKR Inhibition}, author={Jana{\'i}na de F. Fernandes}, booktitle={Biomarkers in cancer}, year={2016} }