OncoScore: a novel, Internet-based tool to assess the oncogenic potential of genes

@article{Rocco2017OncoScoreAN,
  title={OncoScore: a novel, Internet-based tool to assess the oncogenic potential of genes},
  author={Piazza Rocco and Ramazzotti Daniele and Spinelli Roberta and Pirola Alessandra and De Sano Luca and Ferrari Pierangelo and Magistroni Vera and Cordani Nicoletta and Sharma Nitesh and Gambacorti-Passerini Carlo},
  journal={Scientific Reports},
  year={2017},
  volume={7}
}
The complicated, evolving landscape of cancer mutations poses a formidable challenge to identify cancer genes among the large lists of mutations typically generated in NGS experiments. The ability to prioritize these variants is therefore of paramount importance. To address this issue we developed OncoScore, a text-mining tool that ranks genes according to their association with cancer, based on available biomedical literature. Receiver operating characteristic curve and the area under the… 

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