Once-only flexible sigmoidoscopy screening in prevention of colorectal cancer: a multicentre randomised controlled trial
@article{Atkin2010OnceonlyFS, title={Once-only flexible sigmoidoscopy screening in prevention of colorectal cancer: a multicentre randomised controlled trial}, author={W. Atkin and R. Edwards and I. Kralj-Hans and K. Wooldrage and A. Hart and J. Northover and D. Parkin and J. Wardle and S. Duffy and J. Cuzick}, journal={The Lancet}, year={2010}, volume={375}, pages={1624-1633} }
BACKGROUND
Colorectal cancer is the third most common cancer worldwide and has a high mortality rate. We tested the hypothesis that only one flexible sigmoidoscopy screening between 55 and 64 years of age can substantially reduce colorectal cancer incidence and mortality.
METHODS
This randomised controlled trial was undertaken in 14 UK centres. 170 432 eligible men and women, who had indicated on a previous questionnaire that they would accept an invitation for screening, were randomly… CONTINUE READING
Supplemental Presentations
Figures, Tables, and Topics from this paper
Paper Mentions
Interventional Clinical Trial
Participants will be mailed an invitation to complete CRC screening along with a fecal
immunochemical test (FIT) kit, containing a 1-sample "Polymedco Over the Counter (OC) Sensor… Expand
Conditions | Colorectal Cancer |
---|---|
Intervention | Behavioral |
Interventional Clinical Trial
Through this program, the investigators will test a systematic colon cancer screening
outreach strategy for increasing screening completion among uninsured patients, not
up-to… Expand
Conditions | Colorectal Cancer |
---|---|
Intervention | Other |
Interventional Clinical Trial
Guaiac faecal occult blood testing (gFOBT) consistently demonstrates reductions in deaths
from colorectal cancer of around 16% and gFOBT screening is now routine in all four countries… Expand
Conditions | Colorectal Adenoma, Colorectal Cancer |
---|---|
Intervention | Other, Procedure |
1,416 Citations
Once-only sigmoidoscopy in colorectal cancer screening: follow-up findings of the Italian Randomized Controlled Trial--SCORE.
- Medicine
- Journal of the National Cancer Institute
- 2011
- 512
- PDF
Effect of flexible sigmoidoscopy screening on colorectal cancer incidence and mortality: a randomized clinical trial.
- Medicine
- JAMA
- 2014
- 281
- PDF
Invitation for flexible sigmoidoscopy screening reduced colorectal cancer and colorectal cancer mortality
- Medicine
- Annals of Internal Medicine
- 2014
Effectiveness of flexible sigmoidoscopy screening in men and women and different age groups: pooled analysis of randomised trials
- Medicine
- British Medical Journal
- 2017
- 68
- PDF
Long term effects of once-only flexible sigmoidoscopy screening after 17 years of follow-up: the UK Flexible Sigmoidoscopy Screening randomised controlled trial
- Medicine
- The Lancet
- 2017
- 148
Flexible sigmoidoscopy versus faecal occult blood testing for colorectal cancer screening in asymptomatic individuals.
- Medicine
- The Cochrane database of systematic reviews
- 2013
- 174
- PDF
Flexible sigmoidoscopy for colorectal cancer screening: more evidence, persistent ironies.
- Medicine
- JAMA
- 2014
- 9
Colorectal-cancer incidence and mortality with screening flexible sigmoidoscopy.
- Medicine
- The New England journal of medicine
- 2012
- 736
- PDF
Long-term effectiveness of endoscopic screening on incidence and mortality of colorectal cancer: A randomized trial
- Medicine
- United European gastroenterology journal
- 2013
- 7
References
SHOWING 1-10 OF 64 REFERENCES
Single flexible sigmoidoscopy screening to prevent colorectal cancer: baseline findings of a UK multicentre randomised trial
- Medicine
- The Lancet
- 2002
- 343
Risk of colorectal cancer seven years after flexible sigmoidoscopy screening: randomised controlled trial
- Medicine
- BMJ : British Medical Journal
- 2009
- 318
- PDF
Design of a multicentre randomised trial to evaluate flexible sigmoidoscopy in colorectal cancer screening
- Medicine
- Journal of medical screening
- 2001
- 98
Baseline findings of the Italian multicenter randomized controlled trial of "once-only sigmoidoscopy"--SCORE.
- Medicine
- Journal of the National Cancer Institute
- 2002
- 240
- PDF
Flexible sigmoidoscopy in the PLCO cancer screening trial: results from the baseline screening examination of a randomized trial.
- Medicine
- Journal of the National Cancer Institute
- 2005
- 183
- PDF
Uptake, yield of neoplasia, and adverse effects of flexible sigmoidoscopy screening
- Medicine
- Gut
- 1998
- 143
- PDF
A case-control study of screening sigmoidoscopy and mortality from colorectal cancer.
- Medicine
- The New England journal of medicine
- 1992
- 1,686
Uptake of population-based flexible sigmoidoscopy screening for colorectal cancer: a nurse-led feasibility study
- Medicine
- Journal of medical screening
- 2007
- 37
Acceptability of flexible sigmoidoscopy screening in older adults in the United Kingdom
- Medicine
- Journal of medical screening
- 2000
- 39