Once-daily amlodipine in the treatment of mild to moderate hypertension.

@article{Webster1988OncedailyAI,
  title={Once-daily amlodipine in the treatment of mild to moderate hypertension.},
  author={J Webster and O J Robb and Tabatha Jeffers and Arthur Scott and J. C. Petrie},
  journal={Journal of cardiovascular pharmacology},
  year={1988},
  volume={12 Suppl 7},
  pages={S72-5}
}
The antihypertensive efficacy of once-daily amlodipine was studied in a group of 30 patients with mild to moderate hypertension in a double-blind, placebo-controlled, parallel-group study. The dose range of amlodipine was 2.5-10.0 mg daily adjusted every 2 weeks for a total treatment period of 8 weeks. Amlodipine produced a significant reduction in blood pressure compared with placebo, the mean difference between baseline and 8 weeks (corrected for placebo effect) being 16/12 mm Hg supine, 14/4… CONTINUE READING

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