Once-a-month administration of intravenous pentamidine to patients infected with human immunodeficiency virus as prophylaxis for Pneumocystis carinii pneumonia.

@article{Ena1994OnceamonthAO,
  title={Once-a-month administration of intravenous pentamidine to patients infected with human immunodeficiency virus as prophylaxis for Pneumocystis carinii pneumonia.},
  author={Javier Ena and Concepci{\'o}n Amador and Francisco Pasquau and Cristina T. Carbonell and Concepci{\'o}n Benito and F{\'e}lix Guti{\'e}rrez and Andrea Vilar},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={1994},
  volume={18 6},
  pages={901-4}
}
We reviewed the charts of 52 patients infected with human immunodeficiency virus (HIV) who received at least three consecutive doses of intravenous pentamidine as prophylaxis for Pneumocystis carinii infections. Pentamidine isethionate was administered intravenously over 60-90 minutes once a month, at a dosage of 4 mg/kg, in 250 mL of 5% dextrose in water. During 387 months of administration of primary prophylaxis to 37 patients, no cases of P. carinii pneumonia were observed. During 200 months… CONTINUE READING