Once Daily Valacyclovir for Reducing Viral Shedding in Subjects Newly Diagnosed with Genital Herpes

@inproceedings{Martens2009OnceDV,
  title={Once Daily Valacyclovir for Reducing Viral Shedding in Subjects Newly Diagnosed with Genital Herpes},
  author={Mark G. Martens and Kenneth H. Fife and Peter A. Leone and Lynn P. Dix and Clare Brennan},
  booktitle={Infectious diseases in obstetrics and gynecology},
  year={2009}
}
OBJECTIVE Genital herpes (GH) recurrences and viral shedding are more frequent in the first year after initial HSV-2 infection. The objective of this study was to provide the first evaluation of valacyclovir 1 g once daily compared to placebo in reducing viral shedding in subjects newly diagnosed with GH. METHODS 70 subjects were randomized to receive valacyclovir 1 g daily or placebo in a crossover design for 60 days with a 7-day washout period. A daily swab of the genital/anal-rectal area… CONTINUE READING