Onapristone (ZK 98.299): a potential antiprogestin for endometrial contraception.


OBJECTIVES The effects of the antiprogestin onapristone (ZK 98.299) on fertility; menstrual cycle length; duration of menses; serum estradiol, progesterone, and cortisol concentrations; and endometrial morphologic features were studied in adult bonnet monkeys. STUDY DESIGN Five animals were treated subcutaneously with the vehicle and another nine with… (More)


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@article{Katkam1995Onapristone9, title={Onapristone (ZK 98.299): a potential antiprogestin for endometrial contraception.}, author={Rajendra R Katkam and Kamala Gopalkrishnan and Kristof Chwalisz and Eric F J Schillinger and Chander Parkash Puri}, journal={American journal of obstetrics and gynecology}, year={1995}, volume={173 3 Pt 1}, pages={779-87} }