On the use of propensity scores in case of rare exposure.


BACKGROUND Observational post-marketing assessment studies often involve evaluating the effect of a rare treatment on a time-to-event outcome, through the estimation of a marginal hazard ratio. Propensity score (PS) methods are the most used methods to estimate marginal effect of an exposure in observational studies. However there is paucity of data… (More)
DOI: 10.1186/s12874-016-0135-1


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