On the use of multiple probe insertions at the same site for repeated intracerebral microdialysis experiments in the nigrostriatal dopamine system of rats.

@article{Camp1992OnTU,
  title={On the use of multiple probe insertions at the same site for repeated intracerebral microdialysis experiments in the nigrostriatal dopamine system of rats.},
  author={Dianne M. Camp and Terry E. Robinson},
  journal={Journal of neurochemistry},
  year={1992},
  volume={58 5},
  pages={1706-15}
}
The effects of implantation of a dialysis probe into the striatum of awake rats on indices of dopamine (DA) and serotonin neurotransmission were assessed, first over 24 h following initial insertion of a probe, and then again following reinsertion of a probe at the same site 1 week later. It was found that the basal concentration of DA in dialysate stabilized within 20-40 min after probe implantation, although DA showed a modest decline 24 h later. There was, however, no significant difference… CONTINUE READING

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