On the use of Cramér-Rao minimum variance bounds for the design of magnetic resonance spectroscopy experiments


Localized Magnetic Resonance Spectroscopy (MRS) is in widespread use for clinical brain research. Standard acquisition sequences to obtain one-dimensional spectra suffer from substantial overlap of spectral contributions from many metabolites. Therefore, specially tuned editing sequences or two-dimensional acquisition schemes are applied to extend the… (More)
DOI: 10.1016/j.neuroimage.2013.07.062


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