On the ultrastructure of hyalin, a cell adhesion protein of the sea urchin embryo extracellular matrix

@article{Adelson1992OnTU,
  title={On the ultrastructure of hyalin, a cell adhesion protein of the sea urchin embryo extracellular matrix},
  author={D L Adelson and Mary Anne Alliegro and David R. McClay},
  journal={The Journal of Cell Biology},
  year={1992},
  volume={116},
  pages={1283 - 1289}
}
Hyalin is a large (ca. 350 x 10(3) kD by gel electrophoresis) molecule that contributes to the hyalin layer surrounding the sea urchin embryo. In previous work a mAb (McA Tg-HYL), specific for hyalin, was found to inhibit cell-hyalin adhesion and block morphogenesis of whole embryos (Adelson, D. L., and T. D. Humphreys. 1988. Development. 104:391-402). In this report, hyalin ultrastructure was examined via rotary shadowing. Hyalin appeared to be a filamentous molecule approximately 75-nm long… CONTINUE READING