On the sweetness of N-(trifluoroacetyl)aspartame.

@article{Frank2000OnTS,
  title={On the sweetness of N-(trifluoroacetyl)aspartame.},
  author={Michael Frank and David J Aitken},
  journal={Bioscience, biotechnology, and biochemistry},
  year={2000},
  volume={64 9},
  pages={
          1982-4
        }
}
A panel of tasters has found that the N-trifluoroacetyl derivative of aspartame is five times less sweet than the parent compound, contrary to the tenet in the literature, but consistent with sweet receptor models which require this nitrogen to exist in protonated form. 
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