On the structural repertoire of pools of short, random RNA sequences.

@article{Stich2008OnTS,
  title={On the structural repertoire of pools of short, random RNA sequences.},
  author={Michael Stich and Carlos Briones and Susanna C. Manrubia},
  journal={Journal of theoretical biology},
  year={2008},
  volume={252 4},
  pages={750-63}
}
A detailed knowledge of the mapping between sequence and structure spaces in populations of RNA molecules is essential to better understand their present-day functional properties, to envisage a plausible early evolution of RNA in a prebiotic chemical environment and to improve the design of in vitro evolution experiments, among others. Analysis of natural RNAs, as well as in vitro and computational studies, show that certain RNA structural motifs are much more abundant than others, pointing… CONTINUE READING

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