On the safety of a new generation of DSM Aspergillus niger enzyme production strains.

@article{Dijck2003OnTS,
  title={On the safety of a new generation of DSM Aspergillus niger enzyme production strains.},
  author={Piet W M van Dijck and Gerard C M Selten and Rixta A Hempenius},
  journal={Regulatory toxicology and pharmacology : RTP},
  year={2003},
  volume={38 1},
  pages={27-35}
}
Consumers safety of enzyme preparations is determined by three variables: the producing organism, the raw materials used in the production, and the production process itself. The latter one is embedded in current Good Manufacturing Practice (cGMP) and Hazard Analysis of Critical Control Points (HACCP); therefore the safety focus can be directed to raw materials and the producing organism. In this paper, we describe the use of novel genetically modified strains of Aspergillus niger-made by a… CONTINUE READING

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