On the role of mechanosensitive mechanisms eliciting reactive hyperemia.

  title={On the role of mechanosensitive mechanisms eliciting reactive hyperemia.},
  author={A. E. Koller and Zsolt Bagi},
  journal={American journal of physiology. Heart and circulatory physiology},
  volume={283 6},
We hypothesized that changes in hemodynamic forces such as pressure (P) and flow (F) contribute importantly to the development of reactive hyperemia. To exclude the effects of vivo factors, isolated rat skeletal muscle arterioles ( approximately 130 microm) were utilized. We found that changes in P or P + F following occlusions elicited reactive dilations (RD). The peak of RD (up to approximately 45 microm), but not the duration of RD, increased to changes in P (80 to 10, then back to 80 mmHg… CONTINUE READING
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